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Levodopa-dyskinesia incidence by age of Parkinson's disease onset

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Levodopa-dyskinesia incidence by age of Parkinson's disease onset

Auteurs : Neeraj Kumar [États-Unis] ; Jay A. Van Gerpen [États-Unis] ; James H. Bower [États-Unis] ; J. Eric Ahlskog [États-Unis]

Source :

Movement disorders [ 0885-3185 ] ; 2004.

RBID : Pascal:05-0224654

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Lévodopa, Incidence, Dyskinésie, Age apparition, Parkinson maladie.

English descriptors

KwdEn :
- Age of onset, Dyskinesia, Incidence, Levodopa, Nervous system diseases, Parkinson disease.

Abstract

We assessed the 5-year risk of levodopa-induced dyskinesias by age of Parkinson's disease (PD) onset in a population-based cohort. The medical records linkage system of the Rochester Epidemiology project was used to identify residents of Olmsted County, Minnesota, with incident PD for the period 1976 through 1990. In this population-based study, the 5-year dyskinesia incidence declined with age. With PD onset after 70 years of age, the incidence was 16%. With onset from 40 to 59 years of age, the incidence was higher at 50%. These incidence data may overestimate the functional importance, because patients with minimal or reversible dyskinesias were counted.

Affiliations:

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Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age of onset</term>
<term>Dyskinesia</term>
<term>Incidence</term>
<term>Levodopa</term>
<term>Nervous system diseases</term>
<term>Parkinson disease</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Lévodopa</term>
<term>Incidence</term>
<term>Dyskinésie</term>
<term>Age apparition</term>
<term>Parkinson maladie</term>
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<front><div type="abstract" xml:lang="en">We assessed the 5-year risk of levodopa-induced dyskinesias by age of Parkinson's disease (PD) onset in a population-based cohort. The medical records linkage system of the Rochester Epidemiology project was used to identify residents of Olmsted County, Minnesota, with incident PD for the period 1976 through 1990. In this population-based study, the 5-year dyskinesia incidence declined with age. With PD onset after 70 years of age, the incidence was 16%. With onset from 40 to 59 years of age, the incidence was higher at 50%. These incidence data may overestimate the functional importance, because patients with minimal or reversible dyskinesias were counted.</div>
</front>
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<name sortKey="Van Gerpen, Jay A" sort="Van Gerpen, Jay A" uniqKey="Van Gerpen J" first="Jay A." last="Van Gerpen">Jay A. Van Gerpen</name>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Levodopa-dyskinesia incidence by age of Parkinson's disease onset

Levodopa-dyskinesia incidence by age of Parkinson's disease onset

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri